WINSTON-SALEM, N.C. — Clemson quarterback Trevor Lawrence said he's worked this offseason on being patient and taking what the defense is giving him instead of looking for the big play.

It paid off Saturday night.

Lawrence completed 22 of 28 passes for 351 yards and combined for three touchdowns, and the No. 1 Tigers continued their domination of Wake Forest with a 37-13 victory in the season opener for both teams.

"Don't try to do do much," Lawrence said. "Just trust it and go through my progressions."

Travis Etienne ran for 102 yards and a touchdown for Clemson, which improved to 70-5 since the start of the 2015 season under coach Dabo Swinney.

"I knew it was probably going to get a little sloppy, but that's going to make our team better. But Trevor was amazing. He really was," Swinney said.

The Heisman Trophy hopeful looked in solid form against the Demon Deacons.

After going three-and-out with a bad 16-yard sack on the first drive, Clemson scored on its next three possessions, including a pair of short walk-in touchdowns by Lawrence to take a 17-0 lead. On both occasions, the Demon Deacons sold out on the fake handoff to Etienne, allowing Lawrence a free path to the end zone.

Clemson has now outscored Wake Forest 152-19 over the last three seasons, holding the Demon Deacons to just one touchdown. The Tigers have won 12 straight against the Demon Deacons.

Etienne averaged nearly 6 yards per carry and repeatedly picked up yards after initial contact by breaking tackles.

"As he's gotten stronger it has come a little easier for him," Clemson offensive coordinator Tony Elliott said. "He has the best contact balance of any guy I've ever coached."

Lawrence completed 22 of 28 passes and spread the ball around to eight different receivers in the first half alone as Clemson took a 27-0 lead.